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Health Benefits of Pistachios 1. Pistachios are high in fiber, which is good for your gut bacteria. Eating pistachios may increase the number of bacteria that produce beneficial short-chain fatty acids like butyrate. 2. Studies show that eating pistachios may help lower blood cholesterol. It may also lower blood pressure more than other nuts. 3. Pistachio nuts may play an important role in promoting blood vessel health. That’s because they are rich in L-arginine, which, when converted into nitric oxide, helps dilate your blood vessels. 4. Pistachios have a low glycemic index, which might promote lower blood sugar levels. 5. Besides being a great snack, pistachios can be used in baking and cooking, adding a green or purple color to various dishes.